Dynamics of microtubule instabilities
نویسندگان
چکیده
منابع مشابه
Dynamics of Microtubule Instabilities.
We investigate an idealized model of microtubule dynamics that involves: (i) attachment of guanosine triphosphate (GTP) at rate λ, (ii) conversion of GTP to guanosine diphosphate (GDP) at rate 1, and (iii) detachment of GDP at rate μ. As a function of these rates, a microtubule can grow steadily or its length can fluctuate wildly. For μ = 0, we find the exact tubule and GTP cap length distribut...
متن کاملInstabilities in population dynamics
Biologists have long known that the smaller the population, the more susceptible it is to extinction from various causes. Biologists define minimum viable population size (MVP), which is the critical population size, below which the population has a very small chance to survive. There are several theoretical models for predicting the probability that a small population will become extinct. But ...
متن کاملMicrotubule dynamics.
Microtubules are highly dynamic and switch stochastically between growing and shrinking phases both in vivo and in vitro. This non-equilibrium behavior, known as dynamic instability, is based on the binding and hydrolysis of GTP at the nucleotide exchangeable site (E-site) in β-tubulin. Only dimers that have GTP in their E-site can polymerize (red tubulin subunits), but following polymerization...
متن کاملMicrotubule polymerization dynamics.
The polymerization dynamics of microtubules are central to their biological functions. Polymerization dynamics allow microtubules to adopt spatial arrangements that can change rapidly in response to cellular needs and, in some cases, to perform mechanical work. Microtubules utilize the energy of GTP hydrolysis to fuel a unique polymerization mechanism termed dynamic instability. In this review,...
متن کاملDynamics and Instabilities of Nuclear Fermi Liquid
The kinetic theory of Fermi liquid is applied to finite nuclei. The nuclear collective dynamics is treated in terms of the observable variables: particle density, current density, pressure etc. The relaxation processes and the development of instabilities in nuclear Fermi-liquid drop are strongly influenced by the Fermi-surface distortion effects. PACS numbers: 21.60.-n,21.60.Ev,24.30Cz Typeset...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Statistical Mechanics: Theory and Experiment
سال: 2007
ISSN: 1742-5468
DOI: 10.1088/1742-5468/2007/05/l05004